Medical Question & AnswersCategory: MedicinesLoss of neurons or receptors from Haloperidol?
Marek Kašperlík asked 7 years ago

I’ve been misdiagnosed and treated with Haloperidol + Zyprexa together, both orally for 21 days.
Doses of Haloperidol were:
2 days of 3×1.5 mg
15 days of 2+2+3mg
4 days of 1.5+1.5+3mg
Olanzapine: 5 or 10mg
I’m afraid that it might have caused loss of neurons/receptors (especially dopaminergic ones) due to apoptosis/necrosis/oxidative stress… How many neurons could be lost? I know that people can fully recover from 1-2x 5mg of Haloperidol, but what about this? Before this treatment I was prescribed Lisuride (dopamine agonist) and I had very vivid dreams. When I took Lisuride shortly after the treatment with Haloperidol, my dreams were so much less vivid and so weak compared to that. Does it mean that some amount of neurons or receptors were lost? After treatment I also almost lost my ability to sleep and I have to use Agomelatine to sleep 8 hours. My memory is seriously affected, as well as my sleep, perception, wakefulness, energy, libido, and cognitive abilities. Can you, pretty please, compare this treatment with a treatment with just 1-2 5mg of haloperidol, regarding to loss of neurons/receptors? Please do it for me, please.

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