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                    In Vitro Fertilization (IVF)

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How Does the In Vitro Fertilization (IVF) Process Work?

For pregnancy to occur naturally, an egg must be released from the ovary and united with a sperm. Fertilization normally occurs within a fallopian tube, which connects the uterus to an ovary. To understand IVF, it is helpful to understand the normal 28-day menstrual cycle.

With IVF, however, the union occurs in a laboratory after the eggs and sperm have been collected. Simply put, an IVF cycle is an exaggeration of the first half of your regular menstrual cycle, the follicular phase. The same things that occur during a normal menstrual cycle occur in an IVF cycle, and in the same order. However, instead of one follicle producing one egg, the goal is to stimulate multiple follicles in both ovaries, thereby producing multiple eggs.

The big difference between an IVF cycle and a regular menstrual cycle is that ovulation does not take place in an IVF cycle. Instead, the eggs are retrieved at the point of maturation and are fertilized in the IVF lab. Embryos are then transferred to the uterus to initiate a pregnancy. Once the embryos are transferred back into the uterus, there is nothing distinguishable between embryos fertilized in the body or in an IVF laboratory.

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Below are the five major steps of the IVF process in more detail:

Monitor the development of ripening egg(s) in the ovaries. Fertility medications are prescribed to control the timing of egg ripening and to increase the chance of collecting multiple eggs. To monitor egg development, GIVF utilizes ultrasound examinations of the ovaries (a painless method of imaging the enlarging follicles containing the eggs) and the measurement of serial blood hormone levels. An injection of the hormone HCG is then precisely timed to cause final ripening of the eggs.

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Collect eggs. Retrieval of the eggs is performed transvaginally using a hollow needle guided by the ultrasound image, in a completely comfortable procedure under sedation and local anaesthesia.

Obtain sperm. The eggs aspirated from the ovarian follicles are immediately identified by embryologists and placed with the partner’s or donor’s sperm, which will have been carefully processed. If the sperm is considered less likely than usual to achieve fertilization, intracytoplasmic sperm injection (ICSI) into each egg is performed using special micromanipulation equipment.

Place eggs and sperm together in the laboratory, and provide correct conditions for fertilization and early embryo growth. The sperm and eggs are placed into incubators and examined carefully at intervals to ensure that fertilization and cell division have taken place, after which the fertilized eggs are then known as embryos.

Transfer embryos into the uterus. Two to five days after egg retrieval, embryos are ready to be placed in the woman’s uterus. Transfer of embryos at about 5 days post-retrieval is often referred to as blastocyst transfer. A speculum is inserted into the entrance of the uterus and the embryos, suspended in a tiny drop of fluid, are very gently introduced through a catheter into the womb, often under ultrasound guidance. The embryo transfer is followed by a brief period of rest. Subsequent blood tests and ultrasound examinations are used to determine if pregnancy has been successfully established.

 IVF Package In India Details

  • Rates for basic IVF treatmentFor one IVF session, the average cost of treatment in India is approximately 4000 US Dollars. This is not fixed, as it is possible that the rate can go up as high as 8000 US Dollars for one cycle of the treatment.
  • Rates for Any Advanced TreatmentsIf a patient requires advanced technological assistance in IVF, the cost can go much higher. For instance, an ICSI treatment will require an additional 1,500 US Dollars to 4000 US Dollars. A FET (Frozen Embryo Transfer) procedure will cost patients about 1000 US Dollars, apart from the IVF cost in India. Infertility specialists in IVF clinics in India have the ability and technology to provide satisfactory solutions for infertility. With so many reputed centres in different cities across the country, patients can increase their chances of conceiving. By this, they can realize their dream of becoming happy parents of a beautiful and healthy baby!

Click for more info : In Vitro Fertilization Treatment in India

Below are the five major steps of the IVF process in more detail:

  1. Monitor the development of ripening egg(s) in the ovaries. Fertility medications are prescribed to control the timing of egg ripening and to increase the chance of collecting multiple eggs. To monitor egg development, GIVF utilizes ultrasound examinations of the ovaries (a painless method of imaging the enlarging follicles containing the eggs) and the measurement of serial blood hormone levels. An injection of the hormone HCG is then precisely timed to cause final ripening of the eggs.
  2. Collect eggs. Retrieval of the eggs is performed transvaginally using a hollow needle guided by the ultrasound image, in a completely comfortable procedure under sedation and local anaesthesia.
  3. Obtain sperm. The eggs aspirated from the ovarian follicles are immediately identified by embryologists and placed with the partner’s or donor’s sperm, which will have been carefully processed.  If the sperm is considered less likely than usual to achieve fertilization, intracytoplasmic sperm injection (ICSI) into each egg is performed using special micromanipulation equipment.
  4. Place eggs and sperm together in the laboratory, and provide correct conditions for fertilization and early embryo growth. The sperm and eggs are placed into incubators and examined carefully at intervals to ensure that fertilization and cell division have taken place, after which the fertilized eggs are then known as embryos.
  5. Transfer embryos into the uterus.  Two to five days after egg retrieval, embryos are ready to be placed in the woman’s uterus.  Transfer of embryos at about 5 days post-retrieval is often referred to as blastocyst transfer.  A speculum is inserted into the entrance of the uterus and the embryos, suspended in a tiny drop of fluid, are very gently introduced through a catheter into the womb, often under ultrasound guidance. The embryo transfer is followed by a brief period of rest. Subsequent blood tests and ultrasound examinations are used to determine if pregnancy has been successfully established.

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